Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats

BACKGROUND: Insulin resistance (IR) is closely associated with the progression of hepatocellular carcinoma (HCC). Acyclic retinoid (ACR) targets retinoid X receptor α and reportedly prevents HCC recurrence in clinical practice. Angiotensin-II receptor blocker (ARB) can also inhibit experimental hepa...

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Detalles Bibliográficos
Autores principales: Nishimura, Norihisa, Kaji, Kosuke, Kitade, Mitsuteru, Aihara, Yosuke, Sato, Shinya, Seki, Kenichiro, Sawada, Yasuhiko, Takaya, Hiroaki, Okura, Yasushi, Kawaratani, Hideto, Moriya, Kei, Namisaki, Tadashi, Mitoro, Akira, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260898/
https://www.ncbi.nlm.nih.gov/pubmed/30477453
http://dx.doi.org/10.1186/s12885-018-5099-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260898/
https://www.ncbi.nlm.nih.gov/pubmed/30477453
http://dx.doi.org/10.1186/s12885-018-5099-6

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