SIRT1 deacetylase in aging‐induced neuromuscular degeneration and amyotrophic lateral sclerosis

SIRT1 is an NAD(+)‐dependent deacetylase that functions in a variety of cells and tissues to mitigate age‐associated diseases. However, it remains unknown if SIRT1 also acts to prevent pathological changes that accrue in motor neurons during aging and amyotrophic lateral sclerosis (ALS). In this stu...

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Detalles Bibliográficos
Autores principales: Herskovits, Adrianna Z., Hunter, Tegan A., Maxwell, Nicholas, Pereira, Katherine, Whittaker, Charles A., Valdez, Gregorio, Guarente, Leonard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920/
https://www.ncbi.nlm.nih.gov/pubmed/30295421
http://dx.doi.org/10.1111/acel.12839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920/
https://www.ncbi.nlm.nih.gov/pubmed/30295421
http://dx.doi.org/10.1111/acel.12839

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