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M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by the histopathological pattern of usual interstitial pneumonia and is associated with a high mortality rate. Recently, lung resident mesenchymal stem cells (LR-MSCs) have been identified as an important contribu...

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Detalles Bibliográficos
Autores principales: Hou, Jiwei, Shi, Jingyan, Chen, Ling, Lv, Zhongyang, Chen, Xiang, Cao, Honghui, Xiang, Zou, Han, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260991/
https://www.ncbi.nlm.nih.gov/pubmed/30470231
http://dx.doi.org/10.1186/s12964-018-0300-8