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Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c

Mycobacterial efflux pumps play a major role in the emergence of antimycobacterial drug resistance. Of particular interest is the proteinaceous multi-drug efflux pump protein Rv1258c that encodes a tetracycline/aminoglycoside resistance (TAP-2)-like efflux pump which is active in susceptible and dru...

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Detalles Bibliográficos
Autores principales: Cloete, Ruben, Kapp, Erika, Joubert, Jacques, Christoffels, Alan, Malan, Sarel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261026/
https://www.ncbi.nlm.nih.gov/pubmed/30475855
http://dx.doi.org/10.1371/journal.pone.0207605