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Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c
Mycobacterial efflux pumps play a major role in the emergence of antimycobacterial drug resistance. Of particular interest is the proteinaceous multi-drug efflux pump protein Rv1258c that encodes a tetracycline/aminoglycoside resistance (TAP-2)-like efflux pump which is active in susceptible and dru...
Autores principales: | Cloete, Ruben, Kapp, Erika, Joubert, Jacques, Christoffels, Alan, Malan, Sarel F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261026/ https://www.ncbi.nlm.nih.gov/pubmed/30475855 http://dx.doi.org/10.1371/journal.pone.0207605 |
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