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Alpha Mangostin Inhibits the Proliferation and Activation of Acetaldehyde Induced Hepatic Stellate Cells through TGF-β and ERK 1/2 Pathways

Liver fibrosis is characterized by excessive accumulation of extracellular matrix in chronic liver injury. Alcohol-induced fibrosis may develop into cirrhosis, one of the major causes of liver disease mortality. Previous studies have shown that alpha mangostin can decrease ratio of pSmad/Smad and pA...

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Detalles Bibliográficos
Autores principales: Lestari, Novriantika, Louisa, Melva, Soetikno, Vivian, Suwana, Averina Geffanie, Ramadhan, Putra Andito, Akmal, Taufiq, Arozal, Wawaimuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261236/
https://www.ncbi.nlm.nih.gov/pubmed/30538742
http://dx.doi.org/10.1155/2018/5360496