Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypesin a Zebrafish Model of 22q11.2 Deletion Syndrome

Microdeletions involving TBX1 result in variable congenital malformations known collectively as 22q11.2 deletion syndrome (22q11.2DS). Tbx1-deficient mice and zebrafish recapitulate several disease phenotypes, including pharyngeal arch artery (PAA), head muscle (HM), and cardiac outflow tract (OFT)...

Descripción completa

Detalles Bibliográficos
Autores principales: Guner-Ataman, Burcu, Manuel González-Rosa, Juan, Shah, Harsh N., Butty, Vincent L., Jeffrey, Spencer, Abrial, Maryline, Boyer, Laurie A., Burns, C. Geoffrey, Burns, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261257/
https://www.ncbi.nlm.nih.gov/pubmed/30067987
http://dx.doi.org/10.1016/j.celrep.2018.06.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261257/
https://www.ncbi.nlm.nih.gov/pubmed/30067987
http://dx.doi.org/10.1016/j.celrep.2018.06.117

Ejemplares similares