Cargando…
Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypesin a Zebrafish Model of 22q11.2 Deletion Syndrome
Microdeletions involving TBX1 result in variable congenital malformations known collectively as 22q11.2 deletion syndrome (22q11.2DS). Tbx1-deficient mice and zebrafish recapitulate several disease phenotypes, including pharyngeal arch artery (PAA), head muscle (HM), and cardiac outflow tract (OFT)...
Autores principales: | Guner-Ataman, Burcu, Manuel González-Rosa, Juan, Shah, Harsh N., Butty, Vincent L., Jeffrey, Spencer, Abrial, Maryline, Boyer, Laurie A., Burns, C. Geoffrey, Burns, Caroline E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261257/ https://www.ncbi.nlm.nih.gov/pubmed/30067987 http://dx.doi.org/10.1016/j.celrep.2018.06.117 |
Ejemplares similares
-
Latent TGFβ-binding proteins 1 and 3 protect the larval zebrafish outflow tract from aneurysmal dilatation
por: Abrial, Maryline, et al.
Publicado: (2022) -
Supracellular organization confers directionality and mechanical potency to migrating pairs of cardiopharyngeal progenitor cells
por: Bernadskaya, Yelena Y, et al.
Publicado: (2021) -
Discoidin-domain receptor coordinates cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors
por: Bernadskaya, Yelena Y., et al.
Publicado: (2019) -
The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse
por: Maruyama, Kazuaki, et al.
Publicado: (2022) -
A single cell transcriptional roadmap for cardiopharyngeal fate diversification
por: Wang, Wei, et al.
Publicado: (2019)