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A new experimental platform facilitates assessment of the transcriptional and chromatin landscapes of aging yeast

Replicative aging of Saccharomyces cerevisiae is an established model system for eukaryotic cellular aging. A limitation in yeast lifespan studies has been the difficulty of separating old cells from young cells in large quantities. We engineered a new platform, the Miniature-chemostat Aging Device...

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Detalles Bibliográficos
Autores principales: Hendrickson, David G, Soifer, Ilya, Wranik, Bernd J, Kim, Griffin, Robles, Michael, Gibney, Patrick A, McIsaac, R Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261268/
https://www.ncbi.nlm.nih.gov/pubmed/30334737
http://dx.doi.org/10.7554/eLife.39911