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Zinc enhances hippocampal long-term potentiation at CA1 synapses through NR2B containing NMDA receptors

The role of zinc (Zn(2+)), a modulator of N-methyl-D-aspartate (NMDA) receptors, in regulating long-term synaptic plasticity at hippocampal CA1 synapses is poorly understood. The effects of exogenous application of Zn(2+) and of chelation of endogenous Zn(2+) were examined on long-term potentiation...

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Detalles Bibliográficos
Autores principales: Sullivan, John A., Zhang, Xiao-lei, Sullivan, Arthur P., Vose, Linnea R., Moghadam, Alexander A., Fried, Victor A., Stanton, Patric K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261414/
https://www.ncbi.nlm.nih.gov/pubmed/30485271
http://dx.doi.org/10.1371/journal.pone.0205907