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Nonpolar residues in the presumptive pore‐lining helix of mechanosensitive channel MSL10 influence channel behavior and establish a nonconducting function

Mechanosensitive (MS) ion channels provide a universal mechanism for sensing and responding to increased membrane tension. MscS‐like (MSL) 10 is a relatively well‐studied MS ion channel from Arabidopsis thaliana that is implicated in cell death signaling. The relationship between the amino acid sequ...

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Detalles Bibliográficos
Autores principales: Maksaev, Grigory, Shoots, Jennette M., Ohri, Simran, Haswell, Elizabeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261518/
https://www.ncbi.nlm.nih.gov/pubmed/30506019
http://dx.doi.org/10.1002/pld3.59