Cargando…

Network assessment of demethylation treatment in melanoma: Differential transcriptome-methylome and antigen profile signatures

BACKGROUND: In melanoma, like in other cancers, both genetic alterations and epigenetic underlie the metastatic process. These effects are usually measured by changes in both methylome and transcriptome profiles, whose cross-correlation remains uncertain. We aimed to assess at systems scale the sign...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Zhijie, Cinti, Caterina, Taranta, Monia, Mattioli, Elisabetta, Schena, Elisa, Singh, Sakshi, Khurana, Rimpi, Lattanzi, Giovanna, Tsinoremas, Nicholas F., Capobianco, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261551/
https://www.ncbi.nlm.nih.gov/pubmed/30485296
http://dx.doi.org/10.1371/journal.pone.0206686