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Network assessment of demethylation treatment in melanoma: Differential transcriptome-methylome and antigen profile signatures
BACKGROUND: In melanoma, like in other cancers, both genetic alterations and epigenetic underlie the metastatic process. These effects are usually measured by changes in both methylome and transcriptome profiles, whose cross-correlation remains uncertain. We aimed to assess at systems scale the sign...
Autores principales: | Jiang, Zhijie, Cinti, Caterina, Taranta, Monia, Mattioli, Elisabetta, Schena, Elisa, Singh, Sakshi, Khurana, Rimpi, Lattanzi, Giovanna, Tsinoremas, Nicholas F., Capobianco, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261551/ https://www.ncbi.nlm.nih.gov/pubmed/30485296 http://dx.doi.org/10.1371/journal.pone.0206686 |
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