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CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes

Obesity is associated with various human disorders, such as type 2 diabetes, cardiovascular diseases, hypertension, and cancers. In this study, we observed that knockout (KO) of CCN5, which encodes a matricellular protein, caused mild obesity in mice. The CCN5 KO mice also exhibited mild diabetes ch...

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Detalles Bibliográficos
Autores principales: Kim, Jihwa, Joo, Sanghyun, Eom, Gwang Hyeon, Lee, Seung Hoon, Lee, Min-Ah, Lee, Miyoung, Kim, Ki Woo, Kim, Do Han, Kook, Hyun, Kwak, Tae Hwan, Park, Woo Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261567/
https://www.ncbi.nlm.nih.gov/pubmed/30485307
http://dx.doi.org/10.1371/journal.pone.0207228