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CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes
Obesity is associated with various human disorders, such as type 2 diabetes, cardiovascular diseases, hypertension, and cancers. In this study, we observed that knockout (KO) of CCN5, which encodes a matricellular protein, caused mild obesity in mice. The CCN5 KO mice also exhibited mild diabetes ch...
Autores principales: | Kim, Jihwa, Joo, Sanghyun, Eom, Gwang Hyeon, Lee, Seung Hoon, Lee, Min-Ah, Lee, Miyoung, Kim, Ki Woo, Kim, Do Han, Kook, Hyun, Kwak, Tae Hwan, Park, Woo Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261567/ https://www.ncbi.nlm.nih.gov/pubmed/30485307 http://dx.doi.org/10.1371/journal.pone.0207228 |
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