Cargando…

Synthetic STARR-seq reveals how DNA shape and sequence modulate transcriptional output and noise

The binding of transcription factors to short recognition sequences plays a pivotal role in controlling the expression of genes. The sequence and shape characteristics of binding sites influence DNA binding specificity and have also been implicated in modulating the activity of transcription factors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schöne, Stefanie, Bothe, Melissa, Einfeldt, Edda, Borschiwer, Marina, Benner, Philipp, Vingron, Martin, Thomas-Chollier, Morgane, Meijsing, Sebastiaan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261644/ https://www.ncbi.nlm.nih.gov/pubmed/30427832 http://dx.doi.org/10.1371/journal.pgen.1007793

Ejemplares similares

Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq
por: Glaser, Laura V, et al.
Publicado: (2021)

Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity
por: Schöne, Stefanie, et al.
Publicado: (2016)

Corrigendum: Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity
por: Schöne, Stefanie, et al.
Publicado: (2016)

Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements
por: Telorac, Jonas, et al.
Publicado: (2016)

Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements
por: Thormann, Verena, et al.
Publicado: (2019)

STARR‐seq and UMI‐STARR‐seq: Assessing Enhancer Activities for Genome‐Wide‐, High‐, and Low‐Complexity Candidate Libraries
por: Neumayr, Christoph, et al.
Publicado: (2019)

Challenges and considerations for reproducibility of STARR-seq assays
por: Das, Maitreya, et al.
Publicado: (2023)

Functional Definition of Thyroid Hormone Response Elements Based on a Synthetic STARR-seq Screen
por: Flamant, Frédéric, et al.
Publicado: (2022)

Global Quantitative Mapping of Enhancers in Rice by STARR-seq
por: Sun, Jialei, et al.
Publicado: (2019)

Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor
por: Birth, Petra, et al.
Publicado: (2017)

ChIP-exo signal associated with DNA-binding motifs provides insight into the genomic binding of the glucocorticoid receptor and cooperating transcription factors
por: Starick, Stephan R., et al.
Publicado: (2015)

STARRPeaker: uniform processing and accurate identification of STARR-seq active regions
por: Lee, Donghoon, et al.
Publicado: (2020)

Correcting signal biases and detecting regulatory elements in STARR-seq data
por: Kim, Young-Sook, et al.
Publicado: (2021)

Glucocorticoid signaling induces transcriptional memory and universally reversible chromatin changes
por: Bothe, Melissa, et al.
Publicado: (2021)

Computational Analysis of Maize Enhancer Regulatory Elements Using ATAC-STARR-seq
por: Marand, Alexandre P.
Publicado: (2023)

Underlying causes for prevalent false positives and false negatives in STARR-seq data
por: Ni, Pengyu, et al.
Publicado: (2023)

Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation
por: Love, Michael I., et al.
Publicado: (2017)

David Starr :el ranger del espacio /
por: Asimov, Isaac, 1920-1992
Publicado: (1976)

Genome‐wide prediction of activating regulatory elements in rice by combining STARR‐seq with FACS
por: Tian, Wei, et al.
Publicado: (2022)

Lucky Starr : el gran sol de Mercurio
por: Asimov, Isaac, 1920-1992
Publicado: (1980)

Uncovering the Starr of the Cell – SUN and KASH Proteins: An Interview with Daniel A. Starr, PhD
por: Bacher, Sarah Z.
Publicado: (2019)

Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites
por: Kulik, Marina, et al.
Publicado: (2021)

STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells
por: Peng, Tianran, et al.
Publicado: (2020)

An unbiased AAV-STARR-seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo
por: Chan, Ya-Chien, et al.
Publicado: (2023)

ATAC-STARR-seq reveals transcription factor–bound activators and silencers within chromatin-accessible regions of the human genome
por: Hansen, Tyler J., et al.
Publicado: (2022)

STARR with Contour® Transtar™: prospective multicentre European study
por: Lenisa, L, et al.
Publicado: (2009)

C. Starr Brewster, M. D., D. D. S.
Publicado: (1842)

Lucky Starr y el gran sol de Mercurio /
por: Asimov, Isaac, 1920-1992
Publicado: (1995)

Quantifying the tissue-specific regulatory information within enhancer DNA sequences
por: Benner, Philipp, et al.
Publicado: (2021)

RSAT peak-motifs: motif analysis in full-size ChIP-seq datasets
por: Thomas-Chollier, Morgane, et al.
Publicado: (2012)

Morphological rectal alterations following STARR performed for obstructed defecation syndrome
por: Reginelli, A, et al.
Publicado: (2011)

Mr. R. N. Starr, in Reply to Dr. Kinglake, on the Obstetric Practice
Publicado: (1816)

49 years of normal functioning Starr–Edwards aortic valve prosthesis
por: Sabouni, Mouhamed Amr, et al.
Publicado: (2020)

Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
por: Zacher, Benedikt, et al.
Publicado: (2010)

Laparoscopic approach in a case of retroperitoneal and mesorectal haematoma following STARR procedure
por: Cerullo, Guido, et al.
Publicado: (2014)

Functional assessment of human enhancer activities using whole-genome STARR-sequencing
por: Liu, Yuwen, et al.
Publicado: (2017)

1378. Seroprevalence and risk factors for cysticercosis in Mexican-Americans in Starr County, Texas
por: Duffey, Megan M, et al.
Publicado: (2023)

Predicting enhancers in mammalian genomes using supervised hidden Markov models
por: Zehnder, Tobias, et al.
Publicado: (2019)

Stapled Transanal Rectal Resection (Starr) in the Treatment of Obstructed Defecation: A Systematic Review
por: Ripamonti, Lorenzo, et al.
Publicado: (2022)

Bentall procedure 39 years after implantation of a Starr-Edwards Aortic Caged- Ball-Valve Prosthesis
por: Schmitto, Jan D, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_t19oo5krcu1p49uiu4oc8tk9ci