A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

Lysine methylation is a key regulator of histone protein function. Beyond histones, few connections have been made to the enzymes responsible for the deposition of these posttranslational modifications. Here, we debut a high-throughput functional proteomics platform that maps the sequence determinan...

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Detalles Bibliográficos
Autores principales: Cornett, Evan M., Dickson, Bradley M., Krajewski, Krzysztof, Spellmon, Nicholas, Umstead, Andrew, Vaughan, Robert M., Shaw, Kevin M., Versluis, Philip P., Cowles, Martis W., Brunzelle, Joseph, Yang, Zhe, Vega, Irving E., Sun, Zu-Wen, Rothbart, Scott B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261651/
https://www.ncbi.nlm.nih.gov/pubmed/30498785
http://dx.doi.org/10.1126/sciadv.aav2623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261651/
https://www.ncbi.nlm.nih.gov/pubmed/30498785
http://dx.doi.org/10.1126/sciadv.aav2623

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