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An axon initial segment is required for temporal precision in action potential encoding by neuronal populations

Central neurons initiate action potentials (APs) in the axon initial segment (AIS), a compartment characterized by a high concentration of voltage-dependent ion channels and specialized cytoskeletal anchoring proteins arranged in a regular nanoscale pattern. Although the AIS was a key evolutionary i...

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Detalles Bibliográficos
Autores principales: Lazarov, Elinor, Dannemeyer, Melanie, Feulner, Barbara, Enderlein, Jörg, Gutnick, Michael J., Wolf, Fred, Neef, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261658/
https://www.ncbi.nlm.nih.gov/pubmed/30498783
http://dx.doi.org/10.1126/sciadv.aau8621