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Pimavanserin for Parkinson's Disease psychosis: Effects stratified by baseline cognition and use of cognitive‐enhancing medications

Background: PD psychosis is often associated with cognitive impairment, including dementia, and involves dopaminergic, serotonergic, and cholinergic mechanisms. Objective: To evaluate the differential effect of the antipsychotic pimavanserin, a selective serotonin 2A receptor inverse agonist, in PD...

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Detalles Bibliográficos
Autores principales: Espay, Alberto J., Guskey, Michael T., Norton, James C., Coate, Bruce, Vizcarra, Joaquin A., Ballard, Clive, Factor, Stewart A., Friedman, Joseph H., Lang, Anthony E., Larsen, Niccole J., Andersson, Candace, Fredericks, Doral, Weintraub, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261678/
https://www.ncbi.nlm.nih.gov/pubmed/30387904
http://dx.doi.org/10.1002/mds.27488