Cargando…
Interactive calculator for operating characteristics of phase I cancer clinical trials using standard 3+3 designs
Among various Phase I clinical trial designs, rule-based standard 3 + 3 designs are the most widely utilized for their simplicity and robustness. It is necessary to define crucial operating characteristics of a Phase I clinical trial before it starts. Based on the assumed probability of dose limitin...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261803/ https://www.ncbi.nlm.nih.gov/pubmed/30533550 http://dx.doi.org/10.1016/j.conctc.2018.10.006 |