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Increased posterior default mode network activity and structural connectivity in young adult APOE-ε4 carriers: a multimodal imaging investigation

Young adult APOE-ε4 carriers show increased activity in posterior regions of the default mode network (pDMN), but how this is related to structural connectivity is unknown. Thirty young adults (one half of whom were APOE-ε4 carriers; mean age 20 years) were scanned using both diffusion and functiona...

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Detalles Bibliográficos
Autores principales: Hodgetts, Carl J., Shine, Jonathan P., Williams, Huw, Postans, Mark, Sims, Rebecca, Williams, Julie, Lawrence, Andrew D., Graham, Kim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261847/
https://www.ncbi.nlm.nih.gov/pubmed/30339963
http://dx.doi.org/10.1016/j.neurobiolaging.2018.08.026