A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells

Bispecific T cell engager (BiTE) antibody constructs are successfully used as cancer therapeutics. We hypothesized that this treatment strategy could also be applicable for therapy of human cytomegalovirus (HCMV) infection, since HCMV-encoded proteins are abundantly expressed on the surface of infec...

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Detalles Bibliográficos
Autores principales: Brey, Charlotte U., Proff, Julia, Teufert, Natascha, Salzer, Benjamin, Brozy, Johannes, Münz, Markus, Pendzialek, Jochen, Ensser, Armin, Holter, Wolfgang, Lehner, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261951/
https://www.ncbi.nlm.nih.gov/pubmed/30487534
http://dx.doi.org/10.1038/s41598-018-36055-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261951/
https://www.ncbi.nlm.nih.gov/pubmed/30487534
http://dx.doi.org/10.1038/s41598-018-36055-2

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