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CLIP-170 is essential for MTOC repositioning during T cell activation by regulating dynein localisation on the cell surface

The microtubule-organizing centre (MTOC) is repositioned to the centre of the contacted cell surface, the immunological synapse, during T cell activation. However, our understanding of its molecular mechanism remains limited. Here, we found that the microtubule plus-end tracking cytoplasmic linker p...

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Detalles Bibliográficos
Autores principales: Lim, Wei Ming, Ito, Yuma, Sakata-Sogawa, Kumiko, Tokunaga, Makio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261991/
https://www.ncbi.nlm.nih.gov/pubmed/30487641
http://dx.doi.org/10.1038/s41598-018-35593-z