Synergistic enzymatic and bioorthogonal reactions for selective prodrug activation in living systems

Adverse drug reactions (ADRs) restrict the maximum doses applicable in chemotherapy, which leads to failure in cancer treatment. Various approaches, including nano-drug and prodrug strategies aimed at reducing ADRs, have been developed, but these strategies have their own pitfalls. A renovated strat...

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Detalles Bibliográficos
Autores principales: Yao, Qingxin, Lin, Feng, Fan, Xinyuan, Wang, Yanpu, Liu, Ye, Liu, Zhaofei, Jiang, Xingyu, Chen, Peng R., Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261997/
https://www.ncbi.nlm.nih.gov/pubmed/30487642
http://dx.doi.org/10.1038/s41467-018-07490-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261997/
https://www.ncbi.nlm.nih.gov/pubmed/30487642
http://dx.doi.org/10.1038/s41467-018-07490-6

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