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Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses

Mice engrafted with components of a human immune system have become widely-used models for studying aspects of human immunity and disease. However, a defined methodology to objectively measure and compare the quality of the human immune response in different models is lacking. Here, by taking advant...

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Detalles Bibliográficos
Autores principales: Douam, Florian, Ziegler, Carly G. K., Hrebikova, Gabriela, Fant, Bruno, Leach, Robert, Parsons, Lance, Wang, Wei, Gaska, Jenna M., Winer, Benjamin Y., Heller, Brigitte, Shalek, Alex K., Ploss, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262001/
https://www.ncbi.nlm.nih.gov/pubmed/30487575
http://dx.doi.org/10.1038/s41467-018-07478-2