Golgi stress mediates redox imbalance and ferroptosis in human cells

Cytotoxic activities of several Golgi-dispersing compounds including AMF-26/M-COPA, brefeldin A and golgicide A have previously been shown to induce autophagy or apoptosis. Here, we demonstrate that these Golgi disruptors also trigger ferroptosis, a non-apoptotic form of cell death characterized by...

Descripción completa

Detalles Bibliográficos
Autores principales: Alborzinia, Hamed, Ignashkova, Tatiana I., Dejure, Francesca R., Gendarme, Mathieu, Theobald, Jannick, Wölfl, Stefan, Lindemann, Ralph K., Reiling, Jan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262011/
https://www.ncbi.nlm.nih.gov/pubmed/30511023
http://dx.doi.org/10.1038/s42003-018-0212-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262011/
https://www.ncbi.nlm.nih.gov/pubmed/30511023
http://dx.doi.org/10.1038/s42003-018-0212-6

Ejemplares similares