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The phospholipid PI(3,4)P(2) is an apical identity determinant

Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains to perform distinct physiological functions. Cortical lipid asymmetry has emerged as a determinant of cell polarization. We report a network of phosphatidylinositol phosphate (PIP)-modifying enzymes,...

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Detalles Bibliográficos
Autores principales: Román-Fernández, Álvaro, Roignot, Julie, Sandilands, Emma, Nacke, Marisa, Mansour, Mohammed A., McGarry, Lynn, Shanks, Emma, Mostov, Keith E., Bryant, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262019/
https://www.ncbi.nlm.nih.gov/pubmed/30487552
http://dx.doi.org/10.1038/s41467-018-07464-8