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The phospholipid PI(3,4)P(2) is an apical identity determinant
Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains to perform distinct physiological functions. Cortical lipid asymmetry has emerged as a determinant of cell polarization. We report a network of phosphatidylinositol phosphate (PIP)-modifying enzymes,...
Autores principales: | Román-Fernández, Álvaro, Roignot, Julie, Sandilands, Emma, Nacke, Marisa, Mansour, Mohammed A., McGarry, Lynn, Shanks, Emma, Mostov, Keith E., Bryant, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262019/ https://www.ncbi.nlm.nih.gov/pubmed/30487552 http://dx.doi.org/10.1038/s41467-018-07464-8 |
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