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Synaptic Connectivity in Medium Spiny Neurons of the Nucleus Accumbens: A Sex-Dependent Mechanism Underlying Apathy in the HIV-1 Transgenic Rat

Frontal-subcortical circuit dysfunction is commonly associated with apathy, a neuropsychiatric sequelae of human immunodeficiency virus type-1 (HIV-1). Behavioral and neurochemical indices of apathy in the nucleus accumbens (NAc), a key brain region involved in frontal-subcortical circuitry, are inf...

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Detalles Bibliográficos
Autores principales: McLaurin, Kristen A., Cook, Anna K., Li, Hailong, League, Alexis F., Mactutus, Charles F., Booze, Rosemarie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262032/
https://www.ncbi.nlm.nih.gov/pubmed/30524255
http://dx.doi.org/10.3389/fnbeh.2018.00285