Cargando…

Synaptic Connectivity in Medium Spiny Neurons of the Nucleus Accumbens: A Sex-Dependent Mechanism Underlying Apathy in the HIV-1 Transgenic Rat

Frontal-subcortical circuit dysfunction is commonly associated with apathy, a neuropsychiatric sequelae of human immunodeficiency virus type-1 (HIV-1). Behavioral and neurochemical indices of apathy in the nucleus accumbens (NAc), a key brain region involved in frontal-subcortical circuitry, are inf...

Descripción completa

Detalles Bibliográficos
Autores principales:	McLaurin, Kristen A., Cook, Anna K., Li, Hailong, League, Alexis F., Mactutus, Charles F., Booze, Rosemarie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262032/ https://www.ncbi.nlm.nih.gov/pubmed/30524255 http://dx.doi.org/10.3389/fnbeh.2018.00285

Ejemplares similares

Posterior ventral tegmental area-nucleus accumbens shell circuitry modulates response to novelty
por: Li, Hailong, et al.
Publicado: (2019)

Progression of temporal processing deficits in the HIV-1 transgenic rat
por: McLaurin, Kristen A., et al.
Publicado: (2016)

HIV-Associated Apathy/Depression and Neurocognitive Impairments Reflect Persistent Dopamine Deficits
por: McLaurin, Kristen A., et al.
Publicado: (2021)

Unraveling Individual Differences In The HIV-1 Transgenic Rat: Therapeutic Efficacy Of Methylphenidate
por: McLaurin, Kristen A., et al.
Publicado: (2018)

Sex Matters: Robust Sex Differences in Signal Detection in the HIV-1 Transgenic Rat
por: McLaurin, Kristen A., et al.
Publicado: (2017)

Disruption of Timing: NeuroHIV Progression in the Post-cART Era
por: McLaurin, Kristen A., et al.
Publicado: (2019)

Neurodevelopmental Processes in the Prefrontal Cortex Derailed by Chronic HIV-1 Viral Protein Exposure
por: McLaurin, Kristen A., et al.
Publicado: (2021)

Intraneuronal β-Amyloid Accumulation: Aging HIV-1 Human and HIV-1 Transgenic Rat Brain
por: Li, Hailong, et al.
Publicado: (2022)

HIV-1 mRNA Knockdown with CRISPR/Cas9 Enhances Neurocognitive Function
por: McLaurin, Kristen A, et al.
Publicado: (2023)

Microglial HIV-1 Expression: Role in HIV-1 Associated Neurocognitive Disorders
por: Li, Hailong, et al.
Publicado: (2021)

Disrupted Decision-Making: EcoHIV Inoculation in Cocaine Dependent Rats
por: McLaurin, Kristen A., et al.
Publicado: (2022)

HIV-1 and cocaine disrupt dopamine reuptake and medium spiny neurons in female rat striatum
por: Javadi-Paydar, Mehrak, et al.
Publicado: (2017)

The Projection Targets of Medium Spiny Neurons Govern Cocaine-Evoked Synaptic Plasticity in the Nucleus Accumbens
por: Baimel, Corey, et al.
Publicado: (2019)

Neurorestoration of Sustained Attention in a Model of HIV-1 Associated Neurocognitive Disorders
por: Moran, Landhing M., et al.
Publicado: (2019)

Selective Estrogen Receptor β Agonists: a Therapeutic Approach for HIV-1 Associated Neurocognitive Disorders
por: McLaurin, Kristen A., et al.
Publicado: (2019)

SARS-CoV-2 RNA persists in the central nervous system of non-human primates despite clinical recovery
por: Li, Hailong, et al.
Publicado: (2023)

Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens
por: Bessa, J M, et al.
Publicado: (2013)

Presence of Inhibitory Glycinergic Transmission in Medium Spiny Neurons in the Nucleus Accumbens
por: Muñoz, Braulio, et al.
Publicado: (2018)

Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion
por: Soares-Cunha, Carina, et al.
Publicado: (2019)

Binge Alcohol Drinking Alters Synaptic Processing of Executive and Emotional Information in Core Nucleus Accumbens Medium Spiny Neurons
por: Kolpakova, Jenya, et al.
Publicado: (2021)

Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse nucleus accumbens
por: Gangarossa, Giuseppe, et al.
Publicado: (2013)

Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons
por: Kronman, Hope, et al.
Publicado: (2019)

Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain
por: García-González, Diego, et al.
Publicado: (2020)

No Evidence for Sex Differences in the Electrophysiological Properties and Excitatory Synaptic Input onto Nucleus Accumbens Shell Medium Spiny Neurons123
por: Willett, Jaime A., et al.
Publicado: (2016)

S-Equol mitigates motivational deficits and dysregulation associated with HIV-1
por: McLaurin, Kristen A., et al.
Publicado: (2021)

Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro
por: Geldwert, Daron, et al.
Publicado: (2006)

Correction: Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain
por: García-González, Diego, et al.
Publicado: (2021)

Morphine Differentially Alters the Synaptic and Intrinsic Properties of D1R- and D2R-Expressing Medium Spiny Neurons in the Nucleus Accumbens
por: McDevitt, Dillon S., et al.
Publicado: (2019)

Activation of histamine type 2 receptors enhances intrinsic excitability of medium spiny neurons in the nucleus accumbens
por: Aceto, Giuseppe, et al.
Publicado: (2022)

Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens
por: Mizuno, Takeo, et al.
Publicado: (2007)

Drug-primed reinstatement of cocaine seeking in mice: increased excitability of medium-sized spiny neurons in the nucleus accumbens
por: Ma, Yao-Ying, et al.
Publicado: (2013)

Involvement of nucleus accumbens D2–medium spiny neurons projecting to the ventral pallidum in anxiety-like behaviour
por: Correia, Raquel, et al.
Publicado: (2023)

Altered nucleus accumbens functional connectivity precedes apathy in Parkinson’s disease
por: Morris, Lee-Anne, et al.
Publicado: (2023)

PT679. Apathy and striatal dopamine receptor type 2-expressing medium spiny neurons
por: Iku, Tsutsui-Kimura, et al.
Publicado: (2016)

Long-Lasting Alterations in Membrane Properties, K(+) Currents, and Glutamatergic Synaptic Currents of Nucleus Accumbens Medium Spiny Neurons in a Rat Model of Alcohol Dependence
por: Marty, Vincent N., et al.
Publicado: (2012)

Differences in biophysical properties of nucleus accumbens medium spiny neurons emerging from inactivation of inward rectifying potassium currents
por: Steephen, John, et al.
Publicado: (2007)

Prolonged Consumption of Sucrose in a Binge-Like Manner, Alters the Morphology of Medium Spiny Neurons in the Nucleus Accumbens Shell
por: Klenowski, Paul M., et al.
Publicado: (2016)

Chemogenetic selective manipulation of nucleus accumbens medium spiny neurons bidirectionally controls alcohol intake in male and female rats
por: Strong, C. E., et al.
Publicado: (2020)

The estrous cycle and 17β‐estradiol modulate the electrophysiological properties of rat nucleus accumbens core medium spiny neurons
por: Krentzel, Amanda A., et al.
Publicado: (2022)

Subregional Differences in Medium Spiny Neuron Intrinsic Excitability Properties between Nucleus Accumbens Core and Shell in Male Rats
por: Maria-Rios, Cristina E., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_63qq2fkglcbtcsc9s4l8aq9f0b