RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer

Ferroptosis is an iron-dependent, oxidative cell death, and is characterized by iron-dependent accumulation of reactive oxygen species (ROS) within the cell. It has been implicated in various human diseases, including cancer. Recently, ferroptosis, as a non-apoptotic form of cell death, is emerging...

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Detalles Bibliográficos
Autores principales: Sui, Xinbing, Zhang, Ruonan, Liu, Shuiping, Duan, Ting, Zhai, Lijuan, Zhang, Mingming, Han, Xuemeng, Xiang, Yu, Huang, Xingxing, Lin, Haoming, Xie, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262051/
https://www.ncbi.nlm.nih.gov/pubmed/30524291
http://dx.doi.org/10.3389/fphar.2018.01371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262051/
https://www.ncbi.nlm.nih.gov/pubmed/30524291
http://dx.doi.org/10.3389/fphar.2018.01371

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