Inhibitory Effect of Ursodeoxycholic Acid on Clostridium difficile Germination Is Insufficient to Prevent Colitis: A Study in Hamsters and Humans

Introduction: Bile acids (BA) influence germination and growth of Clostridium difficile. Ursodeoxycholic acid (UDCA), a BA minor in human, used for cholestatic liver diseases, inhibits germination and growth of C. difficile in vitro, but was never tested in vivo with an infectious challenge versus c...

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Detalles Bibliográficos
Autores principales: Palmieri, Lola-Jade, Rainteau, Dominique, Sokol, Harry, Beaugerie, Laurent, Dior, Marie, Coffin, Benoit, Humbert, Lydie, Eguether, Thibaut, Bado, André, Hoys, Sandra, Janoir, Claire, Duboc, Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262072/
https://www.ncbi.nlm.nih.gov/pubmed/30524414
http://dx.doi.org/10.3389/fmicb.2018.02849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262072/
https://www.ncbi.nlm.nih.gov/pubmed/30524414
http://dx.doi.org/10.3389/fmicb.2018.02849

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