Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34(+) Cells

Human cytomegalovirus (HCMV) latency is typically harmless but reactivation can be largely detrimental to immune compromised hosts. We modeled latency and reactivation using a traceable HCMV laboratory strain expressing the Gaussia luciferase reporter gene (HCMV/GLuc) in order to interrogate the vir...

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Detalles Bibliográficos
Autores principales: Theobald, Sebastian J., Khailaie, Sahamoddin, Meyer-Hermann, Michael, Volk, Valery, Olbrich, Henning, Danisch, Simon, Gerasch, Laura, Schneider, Andreas, Sinzger, Christian, Schaudien, Dirk, Lienenklaus, Stefan, Riese, Peggy, Guzman, Carlos A., Figueiredo, Constanca, von Kaisenberg, Constantin, Spineli, Loukia M., Glaesener, Stephanie, Meyer-Bahlburg, Almut, Ganser, Arnold, Schmitt, Michael, Mach, Michael, Messerle, Martin, Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262073/
https://www.ncbi.nlm.nih.gov/pubmed/30524448
http://dx.doi.org/10.3389/fimmu.2018.02734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262073/
https://www.ncbi.nlm.nih.gov/pubmed/30524448
http://dx.doi.org/10.3389/fimmu.2018.02734

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