An Experimental Pipeline for Initial Characterization of Bacterial Type III Secretion System Inhibitor Mode of Action Using Enteropathogenic Yersinia

Dozens of Gram negative pathogens use one or more type III secretion systems (T3SS) to disarm host defenses or occupy a beneficial niche during infection of a host organism. While the T3SS represents an attractive drug target and dozens of compounds with T3SS inhibitory activity have been identified...

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Detalles Bibliográficos
Autores principales: Morgan, Jessica M., Lam, Hanh N., Delgado, Jocelyn, Luu, Justin, Mohammadi, Sina, Isberg, Ralph R., Wang, Helen, Auerbuch, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262202/
https://www.ncbi.nlm.nih.gov/pubmed/30524970
http://dx.doi.org/10.3389/fcimb.2018.00404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262202/
https://www.ncbi.nlm.nih.gov/pubmed/30524970
http://dx.doi.org/10.3389/fcimb.2018.00404

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