SGK1-FoxO1 Signaling Pathway Mediates Th17/Treg Imbalance and Target Organ Inflammation in Angiotensin II-Induced Hypertension

It has been demonstrated that serum/glucocorticoid regulated kinase 1 (SGK1) and the downstream transcription factor forkhead box O1 (FoxO1) plays a critical role in the differentiation of T helper 17 cells/regulatory T cells (Th17/Treg). In the present study, we hypothesized that this SGK1-FoxO1 si...

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Detalles Bibliográficos
Autores principales: Du, Ya-Nan, Tang, Xiao-Feng, Xu, Lian, Chen, Wen-Dong, Gao, Ping-Jin, Han, Wei-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262360/
https://www.ncbi.nlm.nih.gov/pubmed/30524295
http://dx.doi.org/10.3389/fphys.2018.01581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262360/
https://www.ncbi.nlm.nih.gov/pubmed/30524295
http://dx.doi.org/10.3389/fphys.2018.01581

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