CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs

CD137 (4-1BB, Tnsfr9) is a member of the TNF-receptor (TNFR) superfamily without known intrinsic enzymatic activity in its cytoplasmic domain. Hence, akin to other members of the TNFR family, it relies on the TNFR-Associated-Factor (TRAF) family of adaptor proteins to build the CD137 signalosome for...

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Detalles Bibliográficos
Autores principales: Zapata, Juan M., Perez-Chacon, Gema, Carr-Baena, Pablo, Martinez-Forero, Ivan, Azpilikueta, Arantza, Otano, Itziar, Melero, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262405/
https://www.ncbi.nlm.nih.gov/pubmed/30524423
http://dx.doi.org/10.3389/fimmu.2018.02618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262405/
https://www.ncbi.nlm.nih.gov/pubmed/30524423
http://dx.doi.org/10.3389/fimmu.2018.02618

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