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A 5-Methylcytosine Site of Growth Differentiation Factor 9 (GDF9) Gene Affects Its Tissue-Specific Expression in Sheep

SIMPLE SUMMARY: Growth differentiation factor 9 (GDF9) is an important gene for ovine fertility. GDF9 is highly expressed in the ovary as opposed to other tissues, but the reason for this is unknown. Our study found this can be caused by the methylation level of the promoter CpG island mC-4 site. Th...

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Detalles Bibliográficos
Autores principales: Pan, Zhangyuan, Wang, Xiangyu, Di, Ran, Liu, Qiuyue, Hu, Wenping, Cao, Xiaohan, Guo, Xiaofei, He, Xiaoyun, Lv, Shengjin, Li, Fukuan, Wang, Hui, Chu, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262488/
https://www.ncbi.nlm.nih.gov/pubmed/30405007
http://dx.doi.org/10.3390/ani8110200