Cargando…

A 5-Methylcytosine Site of Growth Differentiation Factor 9 (GDF9) Gene Affects Its Tissue-Specific Expression in Sheep

SIMPLE SUMMARY: Growth differentiation factor 9 (GDF9) is an important gene for ovine fertility. GDF9 is highly expressed in the ovary as opposed to other tissues, but the reason for this is unknown. Our study found this can be caused by the methylation level of the promoter CpG island mC-4 site. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Zhangyuan, Wang, Xiangyu, Di, Ran, Liu, Qiuyue, Hu, Wenping, Cao, Xiaohan, Guo, Xiaofei, He, Xiaoyun, Lv, Shengjin, Li, Fukuan, Wang, Hui, Chu, Mingxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262488/ https://www.ncbi.nlm.nih.gov/pubmed/30405007 http://dx.doi.org/10.3390/ani8110200

Ejemplares similares

Single Nucleotide Polymorphisms in the HIRA Gene Affect Litter Size in Small Tail Han Sheep
por: Zhou, Mei, et al.
Publicado: (2018)

Whole Genome Sequencing Reveals the Effects of Recent Artificial Selection on Litter Size of Bamei Mutton Sheep
por: Yao, Yaxin, et al.
Publicado: (2021)

Polymorphism Detection of GDF9 Gene and Its Association with Litter Size in Luzhong Mutton Sheep (Ovis aries)
por: Wang, Fengyan, et al.
Publicado: (2021)

Effects of FecB Mutation on Estrus, Ovulation, and Endocrine Characteristics in Small Tail Han Sheep
por: Wang, Xiangyu, et al.
Publicado: (2021)

Expression Analysis of the Prolific Candidate Genes, BMPR1B, BMP15, and GDF9 in Small Tail Han Ewes with Three Fecundity (FecB Gene) Genotypes
por: Tang, Jishun, et al.
Publicado: (2018)

Expression and Functional Analysis of the BCL2-Associated Agonist of Cell Death (BAD) Gene in the Sheep Ovary During the Reproductive Cycle
por: Cao, Xiaohan, et al.
Publicado: (2018)

Molecular Cloning of the B4GALNT2 Gene and Its Single Nucleotide Polymorphisms Association with Litter Size in Small Tail Han Sheep
por: Guo, Xiaofei, et al.
Publicado: (2018)

Rapid evolution of a retro-transposable hotspot of ovine genome underlies the alteration of BMP2 expression and development of fat tails
por: Pan, Zhangyuan, et al.
Publicado: (2019)

Transcriptomic Changes of Photoperiodic Response in the Hypothalamus Were Identified in Ovariectomized and Estradiol-Treated Sheep
por: He, Xiaoyun, et al.
Publicado: (2022)

Metabolic Effects of FecB Gene on Follicular Fluid and Ovarian Vein Serum in Sheep (Ovis aries)
por: Guo, Xiaofei, et al.
Publicado: (2018)

Whole-genome sequences of 89 Chinese sheep suggest role of RXFP2 in the development of unique horn phenotype as response to semi-feralization
por: Pan, Zhangyuan, et al.
Publicado: (2018)

Comparative Transcriptomics Reveal Key Sheep (Ovis aries) Hypothalamus LncRNAs that Affect Reproduction
por: Zhang, Zhuangbiao, et al.
Publicado: (2019)

Genetic diversity and phylogenetic relationship of nine sheep populations based on microsatellite markers
por: Xia, Qing, et al.
Publicado: (2021)

Presence of SNPs in GDF9 mRNA of Iranian Afshari Sheep
por: Eghbalsaied, Shahin, et al.
Publicado: (2012)

Identification and characterization of mRNAs and lncRNAs in the uterus of polytocous and monotocous Small Tail Han sheep (Ovis aries)
por: La, Yongfu, et al.
Publicado: (2019)

Novel Variants in GDF9 Gene Affect Promoter Activity and Litter Size in Mongolia Sheep
por: Tong, Bin, et al.
Publicado: (2020)

Mutations in NLRP5 and NLRP9 Are Associated with Litter Size in Small Tail Han Sheep
por: Zhang, Zhuangbiao, et al.
Publicado: (2020)

Integrated Proteotranscriptomics of the Hypothalamus Reveals Altered Regulation Associated with the FecB Mutation in the BMPR1B Gene That Affects Prolificacy in Small Tail Han Sheep
por: Wang, Xiangyu, et al.
Publicado: (2022)

Differential Expression of Circular RNAs in Polytocous and Monotocous Uterus during the Reproductive Cycle of Sheep
por: La, Yongfu, et al.
Publicado: (2019)

Photoperiod induced the pituitary differential regulation of lncRNAs and mRNAs related to reproduction in sheep
por: He, Xiaoyun, et al.
Publicado: (2021)

Identification of Photoperiod-Induced LncRNAs and mRNAs in Pituitary Pars Tuberalis of Sheep
por: Xia, Qing, et al.
Publicado: (2021)

Integrated Hypothalamic Transcriptome Profiling Reveals the Reproductive Roles of mRNAs and miRNAs in Sheep
por: Zhang, Zhuangbiao, et al.
Publicado: (2020)

Corrigendum: Identification of Photoperiod-Induced LncRNAs and mRNAs in Pituitary Pars Tuberalis of Sheep
por: Xia, Qing, et al.
Publicado: (2021)

A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep
por: Våge, Dag I, et al.
Publicado: (2013)

Litter Size of Sheep (Ovis aries): Inbreeding Depression and Homozygous Regions
por: Tao, Lin, et al.
Publicado: (2021)

Comparative Transcriptomics Reveals the Key lncRNA and mRNA of Sunite Sheep Adrenal Gland Affecting Seasonal Reproduction
por: Du, Xiaolong, et al.
Publicado: (2022)

Polymorphisms of the melatonin receptor 1A gene that affects the reproductive seasonality and litter size in Small Tail Han sheep
por: He, Xiaoyun, et al.
Publicado: (2019)

Expression and functional analysis of the Follistatin‐like 3 (FSTL3) gene in the sheep ovary during the oestrous cycle
por: He, Jianning, et al.
Publicado: (2020)

Comparative Transcriptomics Identify Key Pituitary Circular RNAs That Participate in Sheep (Ovis aries) Reproduction
por: Yang, Jianqi, et al.
Publicado: (2023)

TGIF1 and SF1 polymorphisms are associated with litter size in Small Tail Han sheep
por: Zhang, Zhuangbiao, et al.
Publicado: (2020)

Identification of photoperiod-induced specific miRNAs in the adrenal glands of Sunite sheep (Ovis aries)
por: Du, Xiaolong, et al.
Publicado: (2022)

Insight Into Pituitary lncRNA and mRNA at Two Estrous Stages in Small Tail Han Sheep With Different FecB Genotypes
por: Chen, Si, et al.
Publicado: (2022)

Transcriptome Analysis Revealed Long Non-Coding RNAs Associated with mRNAs in Sheep Thyroid Gland under Different Photoperiods
por: Wang, Wei, et al.
Publicado: (2022)

Epigenetic Regulation of miR-25 and Lnc107153 on Expression of Seasonal Estrus Key Gene CHGA in Sheep
por: Di, Ran, et al.
Publicado: (2023)

Transcriptome Analysis Reveals Differentially Expressed Genes and Long Non-coding RNAs Associated With Fecundity in Sheep Hypothalamus With Different FecB Genotypes
por: Chen, Si, et al.
Publicado: (2021)

Comprehensive Analysis of Differentially Expressed Profiles of mRNA, lncRNA, and circRNA in the Uterus of Seasonal Reproduction Sheep
por: La, Yongfu, et al.
Publicado: (2020)

Luzhong mutton sheep: inbreeding and selection signatures
por: Tao, Lin, et al.
Publicado: (2020)

Single-nucleotide polymorphisms in FLT3, NLRP5, and TGIF1 are associated with litter size in Small-tailed Han sheep
por: Chen, Si, et al.
Publicado: (2021)

An investigation of the effects of BMPR1B, BMP15, and GDF9 genes on litter size in Ramlıç and Dağlıç sheep
por: Çelikeloğlu, Koray, et al.
Publicado: (2021)

Dentinogenesis and Tooth-Alveolar Bone Complex Defects in BMP9/GDF2 Knockout Mice
por: Huang, Xia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cb1g11g7514uu15a9b52a1gl6g