Hydroxysteroid 11-Beta Dehydrogenase 1 Overexpression with Copy-Number Gain and Missense Mutations in Primary Gastrointestinal Stromal Tumors

The lipid-metabolizing enzymes remain underexplored in gastrointestinal stromal tumors (GISTs). Through transcriptomic reappraisal, hydroxysteroid 11-beta dehydrogenase-1 (HSD11B1) was identified as a top-upregulated, progression-associated gene. To validate the clinical relevance of HSD11B1, the in...

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Detalles Bibliográficos
Autores principales: Li, Chien-Feng, Liu, Ting-Ting, Wang, Jui-Chu, Yu, Shih-Chen, Chen, Yen-Yang, Fang, Fu-Min, Li, Wan-Shan, Huang, Hsuan-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262574/
https://www.ncbi.nlm.nih.gov/pubmed/30388854
http://dx.doi.org/10.3390/jcm7110408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262574/
https://www.ncbi.nlm.nih.gov/pubmed/30388854
http://dx.doi.org/10.3390/jcm7110408

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