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Modulation of the CCR6-CCL20 Axis: A Potential Therapeutic Target in Inflammation and Cancer

Prototypical functions of the chemokine receptor CCR6 include immune regulation by maneuvering cell chemotaxis and selective delimiting of the pro-inflammatory T(H)17 and regulatory T(reg) subsets during chronic or acute systemic inflammation. Inhibition of CCR6 is proposed to attenuate disease symp...

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Detalles Bibliográficos
Autores principales: Ranasinghe, Ranmali, Eri, Rajaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262638/
https://www.ncbi.nlm.nih.gov/pubmed/30453514
http://dx.doi.org/10.3390/medicina54050088