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Modulation of the CCR6-CCL20 Axis: A Potential Therapeutic Target in Inflammation and Cancer
Prototypical functions of the chemokine receptor CCR6 include immune regulation by maneuvering cell chemotaxis and selective delimiting of the pro-inflammatory T(H)17 and regulatory T(reg) subsets during chronic or acute systemic inflammation. Inhibition of CCR6 is proposed to attenuate disease symp...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262638/ https://www.ncbi.nlm.nih.gov/pubmed/30453514 http://dx.doi.org/10.3390/medicina54050088 |