YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy

Yes-associated protein (YAP) is an important regulator of cellular proliferation and transdifferentiation. However, little is known about the mechanisms underlying myofibroblast transdifferentiation in dilated cardiomyopathy (DCM). We investigated the role of YAP in the pathological process of cardi...

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Detalles Bibliográficos
Autores principales: Jin, Bo, Zhu, Jun, Shi, Hai-Ming, Wen, Zhi-Chao, Wu, Bang-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262745/
https://www.ncbi.nlm.nih.gov/pubmed/30484494
http://dx.doi.org/10.1590/1414-431X20187914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262745/
https://www.ncbi.nlm.nih.gov/pubmed/30484494
http://dx.doi.org/10.1590/1414-431X20187914

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