Enigma proteins regulate YAP mechanotransduction

Human cells can sense mechanical stress acting upon integrin adhesions and respond by sending the YAP (also known as YAP1) and TAZ (also known as WWTR1) transcriptional co-activators to the nucleus to drive TEAD-dependent transcription of target genes. How integrin signaling activates YAP remains un...

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Detalles Bibliográficos
Autores principales: Elbediwy, Ahmed, Vanyai, Hannah, Diaz-de-la-Loza, Maria-del-Carmen, Frith, David, Snijders, Ambrosius P., Thompson, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262774/
https://www.ncbi.nlm.nih.gov/pubmed/30404826
http://dx.doi.org/10.1242/jcs.221788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262774/
https://www.ncbi.nlm.nih.gov/pubmed/30404826
http://dx.doi.org/10.1242/jcs.221788

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