TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation

TWE-PRIL is a naturally occurring fusion protein of components of two TNF superfamily members: the extracellular domain of APRIL; and the intracellular and transmembrane domains of TWEAK with no known function. Here, we show that April(−/−) mice (which lack APRIL and TWE-PRIL) exhibited overgrowth o...

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Detalles Bibliográficos
Autores principales: Howard, Laura, Wosnitzka, Erin, Okakpu, Darian, White, Matthew A., Wyatt, Sean, Davies, Alun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262789/
https://www.ncbi.nlm.nih.gov/pubmed/30337376
http://dx.doi.org/10.1242/dev.165936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262789/
https://www.ncbi.nlm.nih.gov/pubmed/30337376
http://dx.doi.org/10.1242/dev.165936

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