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TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation
TWE-PRIL is a naturally occurring fusion protein of components of two TNF superfamily members: the extracellular domain of APRIL; and the intracellular and transmembrane domains of TWEAK with no known function. Here, we show that April(−/−) mice (which lack APRIL and TWE-PRIL) exhibited overgrowth o...
Autores principales: | Howard, Laura, Wosnitzka, Erin, Okakpu, Darian, White, Matthew A., Wyatt, Sean, Davies, Alun M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262789/ https://www.ncbi.nlm.nih.gov/pubmed/30337376 http://dx.doi.org/10.1242/dev.165936 |
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