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Long non-coding RNA PICSAR decreases adhesion and promotes migration of squamous carcinoma cells by downregulating α2β1 and α5β1 integrin expression

Long non-coding RNAs (lncRNAs) regulate various cellular processes, and they have emerged as potential biomarkers and therapeutic targets in cancer. We have previously characterized the oncogenic role of lncRNA PICSAR (p38 inhibited cutaneous squamous cell carcinoma associated lincRNA) in cutaneous...

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Detalles Bibliográficos
Autores principales: Piipponen, Minna, Heino, Jyrki, Kähäri, Veli-Matti, Nissinen, Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262852/
https://www.ncbi.nlm.nih.gov/pubmed/30429154
http://dx.doi.org/10.1242/bio.037044