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TUG1 confers cisplatin resistance in esophageal squamous cell carcinoma by epigenetically suppressing PDCD4 expression via EZH2

BACKGROUND: Increasing evidence has suggested the involvement of long non-coding RNA taurine upregulated gene 1 (TUG1) in chemoresistance of cancer treatment. However, its function and molecular mechanisms in esophageal squamous cell carcinoma (ESCC) chemoresistance are still not well elucidated. In...

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Detalles Bibliográficos
Autores principales: Xu, Caihui, Guo, Yinmou, Liu, Haiyan, Chen, Gongbin, Yan, Yanju, Liu, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263046/
https://www.ncbi.nlm.nih.gov/pubmed/30519392
http://dx.doi.org/10.1186/s13578-018-0260-0