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Development and applications of oncolytic Maraba virus vaccines

Oncolytic activity of the MG1 strain of the Maraba vesiculovirus has proven efficacy in numerous preclinical cancer models, and relied not only on a direct cytotoxicity but also on the induction of both innate and adaptive antitumor immunity. To further expand tumor-specific T-cell effector and long...

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Detalles Bibliográficos
Autores principales: Pol, Jonathan G, Atherton, Matthew J, Bridle, Byram W, Stephenson, Kyle B, Le Boeuf, Fabrice, Hummel, Jeff L, Martin, Chantal G, Pomoransky, Julia, Breitbach, Caroline J, Diallo, Jean-Simon, Stojdl, David F, Bell, John C, Wan, Yonghong, Lichty, Brian D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263248/
https://www.ncbi.nlm.nih.gov/pubmed/30538968
http://dx.doi.org/10.2147/OV.S154494