Cargando…

Development and applications of oncolytic Maraba virus vaccines

Oncolytic activity of the MG1 strain of the Maraba vesiculovirus has proven efficacy in numerous preclinical cancer models, and relied not only on a direct cytotoxicity but also on the induction of both innate and adaptive antitumor immunity. To further expand tumor-specific T-cell effector and long...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pol, Jonathan G, Atherton, Matthew J, Bridle, Byram W, Stephenson, Kyle B, Le Boeuf, Fabrice, Hummel, Jeff L, Martin, Chantal G, Pomoransky, Julia, Breitbach, Caroline J, Diallo, Jean-Simon, Stojdl, David F, Bell, John C, Wan, Yonghong, Lichty, Brian D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263248/ https://www.ncbi.nlm.nih.gov/pubmed/30538968 http://dx.doi.org/10.2147/OV.S154494

Ejemplares similares

Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials
por: Pol, Jonathan G., et al.
Publicado: (2018)

Maraba virus-vectored cancer vaccines represent a safe and novel therapeutic option for cats
por: Hummel, Jeff, et al.
Publicado: (2017)

Characterizing Cellular Responses During Oncolytic Maraba Virus Infection
por: Hassanzadeh, Golnoush, et al.
Publicado: (2019)

Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential
por: Tong, Jessica G., et al.
Publicado: (2017)

Enhanced immunotherapeutic profile of oncolytic virus-based cancer vaccination using cyclophosphamide preconditioning
por: Pol, Jonathan G, et al.
Publicado: (2020)

Oncolytic Viruses: Therapeutics With an Identity Crisis
por: Breitbach, Caroline J., et al.
Publicado: (2016)

Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer
por: McGray, A. J. Robert, et al.
Publicado: (2019)

Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8(+) T-cell responses to anticancer vaccines
por: Bridle, Byram W, et al.
Publicado: (2013)

Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
por: Roy, D. G., et al.
Publicado: (2021)

Early and late neuropathological features of meningoencephalitis associated with Maraba virus infection
por: Maia-Farias, A., et al.
Publicado: (2020)

Functional genomic screening to enhance oncolytic virotherapy
por: Mahoney, D J, et al.
Publicado: (2013)

The Role of Neutrophils in Oncolytic Orf Virus-Mediated Cancer Immunotherapy
por: Minott, Jessica A., et al.
Publicado: (2022)

The importance of imaging strategies for pre-clinical and clinical in vivo distribution of oncolytic viruses
por: Pelin, Adrian, et al.
Publicado: (2018)

The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594)
por: Breitbach, Caroline J, et al.
Publicado: (2015)

High-throughput screening to enhance oncolytic virus immunotherapy
por: Allan, KJ, et al.
Publicado: (2016)

Big Data Offers Novel Insights for Oncolytic Virus Immunotherapy
por: Swift, Stephanie L., et al.
Publicado: (2016)

The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers
por: Parato, Kelley A, et al.
Publicado: (2012)

Targeting of Interferon-Beta to Produce a Specific, Multi-Mechanistic Oncolytic Vaccinia Virus
por: Kirn, David H, et al.
Publicado: (2007)

Characterization of the Impact of Oncolytic Vesicular Stomatitis Virus on the Trafficking, Phenotype, and Antigen Presentation Potential of Neutrophils and Their Ability to Acquire a Non-Structural Viral Protein
por: Stegelmeier, Ashley A., et al.
Publicado: (2020)

Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer
por: Crupi, Mathieu J. F., et al.
Publicado: (2022)

Use of Precision-Cut Lung Slices as an Ex Vivo Tool for Evaluating Viruses and Viral Vectors for Gene and Oncolytic Therapy
por: Rosales Gerpe, María C., et al.
Publicado: (2018)

Evidence for differential viral oncolytic efficacy in an in vitro model of epithelial ovarian cancer metastasis
por: Tong, Jessica G, et al.
Publicado: (2015)

Deletion of immunomodulatory genes as a novel approach to oncolytic vaccinia virus development
por: Ho, Tiffany Y., et al.
Publicado: (2021)

Oncolytic Virotherapy as Emerging Immunotherapeutic Modality: Potential of Parvovirus H-1
por: Moehler, Markus, et al.
Publicado: (2014)

Replication and Oncolytic Activity of an Avian Orthoreovirus in Human Hepatocellular Carcinoma Cells
por: Kozak, Robert A., et al.
Publicado: (2017)

Mechanisms that allow vaccination against an oncolytic vesicular stomatitis virus-encoded transgene to enhance safety without abrogating oncolysis
por: AuYeung, Amanda W. K., et al.
Publicado: (2021)

Reovirus FAST Protein Enhances Vesicular Stomatitis Virus Oncolytic Virotherapy in Primary and Metastatic Tumor Models
por: Le Boeuf, Fabrice, et al.
Publicado: (2017)

Activating Peripheral Innate Immunity Enables Safe and Effective Oncolytic Virotherapy in the Brain
por: Balathasan, Lukxmi, et al.
Publicado: (2017)

Exploiting tumor epigenetics to improve oncolytic virotherapy
por: Forbes, Nicole E., et al.
Publicado: (2013)

Ex Vivo Infection of Live Tissue with Oncolytic Viruses
por: Diallo, Jean-Simon, et al.
Publicado: (2011)

ONCOLYTIC VIROTHERAPY
por: Russell, Stephen J, et al.
Publicado: (2012)

Natural killer T cell immunotherapy combined with IL-15-expressing oncolytic virotherapy and PD-1 blockade mediates pancreatic tumor regression
por: Nelson, Adam, et al.
Publicado: (2022)

How Does Severe Acute Respiratory Syndrome-Coronavirus-2 Affect the Brain and Its Implications for the Vaccines Currently in Use
por: Oldfield, Philip R., et al.
Publicado: (2021)

Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages
por: Masemann, Dörthe, et al.
Publicado: (2018)

Advances in oncolytic virotherapy
por: Russell, Stephen J., et al.
Publicado: (2022)

Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers
por: Downs-Canner, Stephanie, et al.
Publicado: (2016)

Oncolytic Viruses in the Treatment of Bladder Cancer
por: Potts, Kyle G., et al.
Publicado: (2012)

Enhancement of Vaccinia Virus Based Oncolysis with Histone Deacetylase Inhibitors
por: MacTavish, Heather, et al.
Publicado: (2010)

Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model
por: Dobson, Christine C, et al.
Publicado: (2016)

Tumor Temperature: Friend or Foe of Virus-Based Cancer Immunotherapy
por: Knapp, Jason P., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_488lgd6sdk4teti47atpoeotbi