High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation

Since the initial description of phage display technology for the generation of human antibodies, a variety of selection methods has been developed. The most critical parameter for all in vitro-based approaches is the quality of the antibody library. Concurrent evolution of the libraries has allowed...

Descripción completa

Detalles Bibliográficos
Autores principales: Ponsel, Dirk, Neugebauer, Julia, Ladetzki-Baehs, Kathrin, Tissot, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263270/
https://www.ncbi.nlm.nih.gov/pubmed/21540796
http://dx.doi.org/10.3390/molecules16053675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263270/
https://www.ncbi.nlm.nih.gov/pubmed/21540796
http://dx.doi.org/10.3390/molecules16053675

Ejemplares similares